Enhancing osteoblast survival through pulsed electrical stimulation and implications for osseointegration

Investigation of the potential of using pulsed electrical stimulation as a means to promote osseointegration in an in vitro model. Three different stimulation treatments were applied in a novel in vitro setup. The findings suggested that pulsed electrical stimulation with characteristics similar to peripheral nerve stimulation has the potential to improve cell survival and may provide a promising approach to improve implant-bone healing, particularly to neuromusculoskeletal interfaces in which implanted electrodes are readily available.